Fields of action
Cytochrome p450 Complex
- CYP2D6
- CYP2C19
- CYP3A5
Tyrosine Kinase Inhibitors
- bcr/abl: Response to Imatinib
Anti-dementia drugs
- APOE
Acetylation
- NAT2
Estrogen replacement therapy
- COMT
Hyperhomocysteinemia Treatment
- MTFHR
- CBS
- MS
SNPs at the Beta-Adrenergic Receptor Level
• Arg16Gly: Response to anti-asthmatic treatment
• Gln27Glu: Obesity
Tyrosine Kinase Inhibitors
• bcr/abl: Response to Imatinib
Analytical techniques
- Gene amplification by PCR: qualitative and quantitative
- RFLP (Restriction Fragment Length Polymorphism)
- SSCP (Single-Strand Conformation Polymorphism)
- DNA sequencing
- Cell cultures
- Nucleic acid hybridization:
- Northern blot (RNA)
- Southern blot (DNA)